Avibactam Impurity 145 CAS 2089462-91-7(free base)
| CAS No. | 2089462-91-7(free base) |
| Molecular Formula | C15H22N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Avibactam Impurity 145 (CAS 2089462-91-7(free base), C15H22N2O3C2H2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C15H22N2O3C2H2O4, Avibactam Impurity 145 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 368.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H22N2O3 C2H2O4 |
| Molecular Weight | 368.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Avibactam Standards
- Avibactam Impurity 133 (CAS 1133931-73-3)
- Avibactam impurity 113 (CAS 115134-37-7)
- Avibactam Impurity 89 (CAS 1171080-45-7)
- Avibactam Impurity 22 (CAS 1174020-25-7)
- Avibactam Sodium Salt (CAS 1192491-61-4)
- Avibactam-13C5,15N Sodium Salt (CAS 1192491-61-4 (non-labelled))
- Avibactam Impurity 02 (CAS 1192500-31-4)
- Avibactam Impurity 56（2S,5R) (CAS 1192651-49-2)
Recommended Standards
- Suzetrigine Impurity 13 (CAS CATO-C4X-336913)
- Paliperidone Impurity 8 (CAS CATO-C4X-17248)
- N-Nitroso-Deferasirox EP Impurity F (CAS CATO-C4X-143823)
- 5-Isothiocyanato-1-methyl-3-trifluoromethyl-1H-pyrazole (CAS 1349717-53-8)
- Methyl 4-((tetrahydrofuran-2-yl)methoxy)benzofuran-6-carboxylate (CAS 1291489-18-3)
- (4,6-Dimethylmorpholin-2-yl)methanol (CAS 1601987-04-5)
- β-oxo-Cyclohexanepropanenitrile (CAS 62455-70-3)
- Flomoxef Impurity 19 (CAS CATO-C4X-138219)
- 7-bromo-6-methoxy-1H-indazole (CAS 1374651-66-7)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
Why CATO?
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